Dr Gautam Allahbadia

Assisted Reproductive Techniques

How ICSI and IVF open the door to parenthood when other procedures fail

In Vitro Fertilisation (IVF) is a procedure commonly used to treat infertility or genetic disorders and assist with the conception of a healthy child. The embryo formed upon the successful fertilization of the egg by the sperm is allowed to develop in the laboratory. It is later transferred into the patient’s uterus, where it will hopefully implant and develop further.

An IVF cycle comprises of five main steps:

1. Controlled Ovarian Hyper-stimulation (COH) and Follicular Monitoring
2. hCG Trigger and Oocyte Retrieval
3. Oocyte Culture, Insemination and Fertilization in the IVF Laboratory
4. Embryo Transfer
5. Luteal Support

This process is taken one step further with the help of Intracytoplasmic Sperm Injection (ICSI). It involves inserting a single sperm directly into the oocyte (cytoplasm of a mature egg) using a microinjection pipette made of glass.

Dr Gautam Allahbadia - ARTThe need for IVF

I suggest undergoing IVF when alternative treatments either fail to result in a pregnancy or are unlikely to achieve the desired results. IVF is best suited for women with blocked fallopian tubes. Patients with extensive pelvic adhesions that prevent the egg from entering the fallopian tubes can also benefit from IVF treatment.
Furthermore, IVF can be especially helpful in case the male partner has low sperm counts. The procedure allows us to super concentrate sperm, thus resulting in potentially successful fertilization. Also, in cases of ‘unexplained’ infertility (where the patient is unable to conceive despite all tests being normal), IVF can be a great option.
I also advise women suffering from Polycystic Ovaries (PCOS) to go for IVF, if ovulation induction has remained unsuccessful for them. IVF can also help in cases of severe Endometriosis. If a patient has mild to moderate Endometriosis, Intrauterine Insemination (IUI) can be tried before proceeding to IVF.

The need for ICSI

Intracytoplasmic Sperm Injection (ICSI) has been a breakthrough procedure for treating male infertility. ICSI is advisable in cases where the male partner’s sperm count or a number of motile sperm is very low, or the morphology is not up to the mark. At Millennium Medical Centre (MMC IVF), we recommend ICSI based on the results of the semen analysis.

What about the extra embryos?

After a successful embryo transfer, the remaining good quality embryos can be frozen through vitrification process. This gives them an excellent survival rate. Women do not require ovarian stimulation and egg retrieval again, making future assisted reproduction cycles simpler, less invasive and more economical than the initial cycle.

Success rates of ICSI and IVF procedures

At MMC IVF, my team works to provide the best success rates across the country. We are constantly upgrading our stimulation procedures, embryo transfer guidelines, and laboratory culture conditions.
The woman’s age and the reason for infertility remain the two most important factors in determining the success of an IVF cycle. Since each patient is unique, we discuss their individual case history before coming up with a treatment plan for them.

Dr. Gautam Allahbadia is an IVF specialist and is a Reproductive Endocrinology and IVF consultant at the Millennium Medical center (MMC IVF) in Dubai. He is also the founder of the Rotunda-The Center for Human Reproduction. A Medical Professional with 25 years of expertise in Assisted Reproductive Techniques (ART), Gautam Allahbadia has played a major role in the setting up and growth of two independent IVF clinics in Mumbai. He is one of the pioneers in Minimal Stimulation IVF (IVF Lite) in South-East Asia. In his prolific career, he has more than 150 peer-reviewed publications to his credit. Dr. Gautam Allahbadia has also authored over 150 scientific papers, 126 book chapters, and 24 textbooks.

8 comments

  1. Shivi Pathak 17 July, 2019 at 06:30 Reply

    Assisted Reproduction is the need of the hour as couples are planning families at a later stage in life and these techniques are mostly used by such couples. Even I began planning my family when I was 39 and faced infertility issues.

  2. Samuel 25 June, 2019 at 05:12 Reply

    IVF is helping infertile women and techniques like ICSI are helping males to counter infertility and experience parenthood. ART has proved to be helping hand to the families who are facing infertility issues.

  3. Piyush Shergil 11 June, 2019 at 04:42 Reply

    The assisted reproductive techniques like IVF and ICSI are a helping hand to infertile couples.

  4. Yash Lamba 6 June, 2019 at 04:59 Reply

    I have read a lot about you sir. You have helped many couples through assisted reproduction and I think these techniques really work well. Thanks for sharing this informational article.

Leave a reply